Dr Kamalesh D Mumbrekar

Associate Professor

Department of Radiation Biology and Toxicology

CURRENT ACADEMIC ROLE & RESPONSIBILITIES

    Kamalesh D Mumbrekar is Associate Professor in the Department of Radiation Biology & Toxicology at Manipal School of Life Sciences.

    He:

    • Teaches theory/practical to BSc, MSc, PG diploma students
    • Guides students (BSc/ MSc) in their project work
    • Participates in ongoing research at the department by writing new grants and publishing the findings
    • Class In-charge for III Year BSc Biotechnology
    • Participates in institutional activities like workshops, science day, inspire program, refresher course etc.
    • Radiation Safety Officer (RSO-1)
    • Internal Auditor- ISO

     

SUBJECTS CURRENTLY TEACHING

Subject Semester / Year
Biology-1 (Theory) BSc, I Semester
Biology-1 (Practical) BSc, I Semester
Cell Biology-1 (Theory) BSc, II Semester
Cell Biology-1 (Practical) BSc, II Semester
Basics of Biotechnology (Theory) BSc Biotechnology, I Semester
Molecular Biology (Practical) BSc, III Semester
Project BSc BSc, VI Semester
Project MSc MSc, IV Semester
Radiobiology First Year BSc MRT
Radiobiology First Year MSc MRP

ACADEMIC QUALIFICATIONS

Degree Specialisation Institute Year of passing
PhD Radiation Biology (Cellular and Molecular Analysis of Normal Tissue Toxicity Induced by Radiotherapy In Breast Cancer Patients) Department of Radion Biology & Toxicology, School of Life Sciences, Manipal University, Manipal 2015
MPhil Zoology Annamalai University, Tamil Nadu 2011

Experience

Institution / Organisation Designation Role Tenure
Division of Radiobiology & Toxicology, School of Life Sciences Assistant Professor October 2015 to present
Division of Radiobiology & Toxicology, School of Life Sciences Lecturer 2008 - 2015
Division of Radiobiology & Toxicology, School of Life Sciences Senior Research Fellow 2007 - 2008

Radiation-induced gut dysbiosis and its effects on the brain Impact of microgravity and space radiation on the brain Long-term effect of low-dose radiation exposure on the brain Bacterial supplements in radiation protection- gut, brain

AREAS OF INTEREST, EXPERTISE AND RESEARCH

Area of Interest

Radiation biology, Toxicology

Area of Expertise

Cellular and molecular Radiobiology, DNA repair, Cellular and molecular Neurotoxicology

Area of Research

Low-dose radiation effects, Non-targeted radiation effects through the gut-brain axis, Space radiation biology, Radiation protection, Biodosimetry

Professional Affiliations & Contributions

  • Life member of Indian Society for Radiation Biologists, India.
  • Life member of Society for Radiation Research, India.
  • Life member of Environmental Mutagen Society of India.
  • Life member Indian Association for Radiation Protection.

Full Publications List

List of Students project

POST GRADUATE THESIS
2024

  1. Impact of Ionizing Radiation on DNA Methylation in the Brain Tissue of Mice
  2. Unveiling the Effects of Pelvic Irradiation on Apoptosis and Mitochondrial Integrity in the Brain via the Gut-Brain Axis
  3. Exploring the Mechanism of Gut Dysbiosis Induced Neuroinflammation
2023
  1. Evaluating the Neuroprotective Potential of Taurine on Rotenone-induced Invitro Parkinson’s Disease Model
  2. Developing Spectroscopic Techniques to Classify the Radiation Exposed Samples for Radiation Biodosimetry Application
2021
  1. Exploring the brain metabolomic changes in response to pesticide and its link with neurodegenerative diseases

2018
  1. Effect of Probiotic Treatment on Radiation-Induced Gut Damage in Mouse Model
  2. Titanium Dioxide Nanoparticle Induced Histological and Biochemical Changes in Mouse Model

2016
  1. Influence of SNPs in Genes Involved in DNA Repair Pathways on the Radiotherapy Induced Acute Skin Toxicity

2014
  1. Role of Single Nucleotide Polymorphism in Breast Cancer Predisposition

2012
  1. Genetic polymorphisms and its role in radiotherapy induced acute skin reactions

2011
  1. Visualization and Counting of Damage-spots in Lymphocyte Nuclei from Fluorescence-Microscope-images
  2. Cellular and Molecular Evaluation of Normal Tissue Acute Skin Reaction Induced by Radiotherapy

2009
  1. 2D Fluorescent Image Analysis for Automation Approach to Quantifying DNA Damages using γ-H2AX

UNDERGRADUATE THESIS SUPERVISED
2024
    Effect of radiation on genes involved in neurodegenerative diseases and DNA repair in Brain Tissue
  1. Effect of low dose Malathion exposure on DNA Methylation related genes in Mice Brain
  2. Three-dimensional bioprinted tissue-engineered dermal construct for toxicological studies
2023
  1. Impact of Microgravity on Genotoxicity of DNA Damaging Agents
  2. Mitigation of Radiation-Induced Gastrointestinal Damage and Inflammation Using Bacterial Supplementation
2022
  1. Does pelvic radiation induce changes in neuronal cell maturation in the dentate gyrus region of a rat model?
  2. Neuroinflammatory potential of organophosphate pesticides (malathion) in mouse
2021
  1. Understanding the mechanism of genotoxicity induced by Malathion in glial cells
  2. The Effect of Antibiotics on the Gut-Brain Axis in rat model
  3. Investigating The Effects of Malathion on Mitochondria in Neuroglial Cells

2020
  1. Understanding the Effect of Environmental Neurotoxicants on the Genes Involved in Neuronal Survival and Plasticity
  2. To Understand the effect of Pesticides on Brain Metabolites in Mouse Model

2019
  1. Mitigation of Cisplatin Induced Cognitive Impairments by Naringenin
  2. Role of Naringinin in Mitigating the Cisplatin Induced Organ Toxicity in Mouse Model

2018
  1. Titanium Dioxide Nanoparticle Exposure and Structural Changes in the Hippocampal Neuron -Preclinical Study